低碳水化合物饮食得分和死亡风险:日本合作队列研究
Tae Sasakabe1, Kenji Wakai2, Sayo Kawai1
1Department of Public Health, Aichi Medical University School of Medicine, Aichi, Japan; Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Aichi, Japan.
The Journal of nutrition
|February 8, 2025
概括
适度低碳水化合物饮食 (LCD) 可能降低日本人口的整体死亡风险. 具体来说,强调鱼类脂肪摄入的饮食显示了与总死亡率的U形关联以及与心血管疾病 (CVD) 死亡率的逆关联.
科学领域:
- 营养流行病学 营养流行病学
- 心血管疾病研究研究
- 公共卫生 营养 公共卫生 营养
背景情况:
- 低碳水化合物饮食 (LCD) 显示出降低心血管疾病 (CVD) 风险因素的潜力.
- 液晶显示屏对死亡率的影响,特别是在饮食模式不同的人群中 (高碳水化合物,低脂肪),需要进一步调查.
研究的目的:
- 调查遵守低碳水化合物饮食 (LCD) 与所有原因和特定原因死亡风险之间的关联.
- 在日本合作队列研究的背景下分析这些关联.
主要方法:
- 对22659名男性和35192名女性 (40-79岁) 的分析,使用来自日本合作队列研究的数据.
- 基于食物频率问卷的LCD分数的构建,按脂肪来源 (动物,鱼,植物) 分类.
- 考克斯的比例危险模型被用来评估液晶显示屏分数与死亡率之间的关联,并对潜在的混因素进行调整.
主要成果:
- 在19年4年的中位数随访期间,记录了10835例死亡.
- 在LCD得分和总死亡率 (HR 0.85;95% CI 0.78-0.93在第八十位数) 之间发现了整体反向关联.
- 基于鱼脂的液晶显示屏分数显示出与总死亡率的U形关联以及与心血管疾病死亡率的反向关联,在两种性别中观察到,特别是在女性中.
结论:
- 适度坚持总体和基于鱼脂的低碳水化合物饮食与日本人口的总死亡风险降低有关.
- 基于鱼脂的液晶显示器显示出与心血管疾病死亡率有显著的反向关联.
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