葡萄球菌骨关节感染的临床和流行病学差异:为开发医院感染控制干预措施的见解
João Figueiredo1,2, Jorge Lindo1,2,3,4, Catarina Chaves5
1FMUC-Faculty of Medicine, University Coimbra, Coimbra, Portugal.
概括
这项研究比较了由黄金葡萄球菌和凝聚酶阴性葡萄球菌 (CoNS) 引起的骨关节感染 (OAI). 研究结果揭示了每个病原体的独特风险因素和抗菌素耐药性模式,为目标治疗策略提供了信息.
科学领域:
- 传染性疾病 传染性疾病
- 微生物学 微生物学
- 整形外科 整形外科 整形外科
背景情况:
- 骨关节感染 (OAI) 是一种严重的疾病,其中金色葡萄球菌和阴性凝固菌葡萄球菌 (CoNS) 导致高达三分之二的病例.
- 了解S. aureus和CoNS引起的OAI之间的差异对于有效的临床管理和感染控制至关重要.
研究的目的:
- 为了比较由S. aureus和CoNS引起的OAI的流行病学,临床和微生物学的特征.
- 提供有助于OAI的临床管理和感染控制的数据.
主要方法:
- 从2011年1月到2021年12月进行了一项单一中心的回顾性研究.
- 用医疗记录和SPSS统计软件分析了458起OAI病例的数据.
主要成果:
- 黄金菌是OAI的60.7%,而S. epidermidis (一种CoNS) 占29.9%.
- 黄金菌的危险因素包括男性性别和骨髓炎病史. CoNS感染与年龄较大,假肢设备和之前的周围假肢感染有关.
- 这两种病原体都表现出显著的抗微生物耐药性,其中CoNS表现出更高的抗 gentamicin,linezolid,teicoplanin 和trimethoprim-sulfamethoxazole,而S. aureus更常见的抗克林达米辛.
结论:
- 由S. aureus和CoNS引起的OAI表现出不同的特征.
- 针对风险因素的有针对性管理和量身定制的经验性抗生素治疗对于减少OAI发生率和改善患者结果至关重要.
相关概念视频
01:22Healthcare Associated Infections II: Preventive Measures
2.4K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.4K
01:26Standard Precaution
1.8K
Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
1.8K
01:26Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
3.9K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
3.9K
01:20Infection
7.1K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
7.1K
01:23Hand hygiene
3.1K
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Hand washing...
3.1K
01:28Asepsis
2.0K
The condition of being free from disease-causing living pathogens is asepsis. Aseptic techniques include a set of standard practices to achieve asepsis. An example is the regular environmental cleaning of all parts of the healthcare facility and hand hygiene at home before preparing or eating food. Medical and surgical asepsis in healthcare practice protects patients from harmful pathogens, minimizes the risk of contamination of susceptible sites, and reduces the risk of infection transmission.
2.0K