睡眠模式和二手烟暴露与非吸烟成年人死亡率的联合效应
Chen Chen1, Hongyu Jin1, Zhiping Jiang1
1Respiratory and Critical Care Department, the First Hospital of China Medical University, Shenyang, China.
概括
不健康的睡眠和二手烟 (SHS) 暴露独立增加死亡风险. 两种因素的结合显著提高了所有原因和心血管疾病 (CVD) 的死亡风险.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 环境健康 环境健康
背景情况:
- 不健康的睡眠和二手烟 (SHS) 暴露是死亡率的独立风险因素.
- 调查它们对所有原因和心血管疾病 (CVD) 死亡率的综合影响对于公共卫生至关重要.
研究的目的:
- 检查不健康睡眠模式和SHS暴露与所有原因和心血管疾病死亡率的独立和联合关联.
- 分析来自全国代表性成年人口的数据.
主要方法:
- 利用了国家健康和营养检查调查 (2005-2014) 中15175名成年人的数据.
- 根据持续时间,睡眠困难和诊断的疾病对睡眠模式进行分类 (健康,中等,不良).
- 在非吸烟者中使用血清丁氨酸水平评估SHS暴露.
- 使用多变量Cox危害回归模型来确定死亡风险.
主要成果:
- 睡眠不足独立地与更高的全因死亡率 (HR 1.32) 和心血管疾病死亡率 (HR 1.31) 有关.
- SHS暴露与所有原因 (HR 1.21) 和心血管疾病死亡率 (HR 1.25) 的增加有关.
- 睡眠不健康和SHS暴露的人面临着显著更高的全因风险 (HR 1.48) 和心血管疾病死亡率 (HR 1.51).
结论:
- 不健康的睡眠模式和SHS暴露的共存显著增加了所有原因和心血管疾病死亡率的风险.
- 睡眠质量和SHS暴露都是可修改的风险因素.
- 针对改善睡眠和减少SHS暴露的干预措施可能会降低死亡率.
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