在患有慢性疾病的老年人中,将营养状况与认知功能联系起来的途径:探索睡眠质量的调解作用
Xiaopan Xu1, Ling Meng2, Yingzhen Wang3
1Department of Respiratory and Critical Care Medicine, Lu'an Hospital of Anhui Medical University, Lu'an, 237005, China.
概括
营养状况影响慢性疾病的老年人认知功能. 睡眠质量不佳部分介导了这种联系,强调了它对大脑健康的重要性.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 营养科学 营养科学
背景情况:
- 认知能力下降是老年人,特别是那些患有慢性疾病的人的重大问题.
- 在这个人群中,营养状况,睡眠质量和认知功能之间的相互作用仍然不完全理解.
研究的目的:
- 研究慢性疾病的老年人营养状况和认知功能之间的关联.
- 检查睡眠质量在这种关系中的潜在调解作用.
主要方法:
- 一项涉及248名患有慢性疾病的老年人的横截面研究.
- 通过调查问卷收集的数据包括迷你营养评估简单表格 (MNA-SF),蒙特利尔认知评估 (MoCA) 和匹兹堡睡眠质量表 (PSQI).
- 统计分析包括线性回归和引导式方法.
主要成果:
- 患有慢性疾病的老年人表现出显著的认知能力下降 (平均MoCA分数=23.60).
- 营养状况受损与认知能力下降的风险增加直接相关 (β = 1.006,P < 0.001).
- 睡眠质量部分介导了营养与认知的联系,解释了17.59%的效果;睡眠不足加剧了认知能力下降的风险.
结论:
- 营养状况显著影响慢性疾病的老年人认知表现,睡眠质量作为部分调解者.
- 保持高质量的睡眠对于在老年人群中保持大脑健康至关重要.
- 针对营养状况和睡眠质量的干预措施可能有助于减缓认知衰退的进展.
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