研究人员的种族多样性和临床试验参与
Marcella Alsan1, Romaine A Campbell2, Lukas Leister3
1Kennedy School of Government, Harvard University, Cambridge, MA 02138, United States of America.
Journal of health economics
|February 8, 2025
概括
黑人患者和临床试验领导人之间的种族一致性增加了对参与研究的兴趣. 这一发现凸显了临床研究多样性的重要性,以改善黑人患者的入学率.
科学领域:
- 临床试验多样性的多样性
- 卫生公平研究 卫生公平研究
- 患者招募策略 患者招募策略
背景情况:
- 在临床试验中,黑人患者的入学率明显落后于人口代表性和疾病负担.
- 主要研究人员之间缺乏多样性可能会导致参与试验的差异.
- 研究人员的特点可以影响患者的招聘和留住.
研究的目的:
- 确定主要研究人员中增加的种族多样性是否提高了临床试验中黑人患者的入学率.
- 检查研究人员种族对黑人患者参与研究的意愿的影响.
- 确定调解研究者种族与患者兴趣之间的关系的因素.
主要方法:
- 进行了一项调查实验,随机选择受访者查看黑人或白人国家卫生研究院 (NIH) 研究人员的图像.
- 调查人员的性别也被随机选择作为比较基准.
- 参与者对临床研究入学的兴趣是根据研究人员的种族和性别一致性进行测量和分析的.
主要成果:
- 黑人受访者报告了0.35标准偏差单位更高的兴趣 (12.6%的增长) 参加由种族一致的研究者领导的研究.
- 调查人员的性别一致性对参与兴趣没有显著影响.
- 研究人员的可信度和吸引力被认为是影响这些结果的关键因素.
结论:
- 主要研究人员和潜在参与者,特别是黑人患者之间的种族一致性显著增加了对临床试验参与的兴趣.
- 在临床试验领导层中增强种族多样性可能是解决黑人患者代表不足问题的关键策略.
- 通过种族一致来建立信任和感知吸引力,对于改善对临床研究的平等准入至关重要.
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