副脊柱肌肉的形态和组成是否与腰椎脊柱狭窄有关? 一个系统的审查
Aliyu Lawan1, Zakari Crites Videman1, Anna Belay1
1School of Physical Therapy, Faculty of Health Sciences, Western University, London, Ontario, Canada.
概括
增加的多体脂肪透与腰椎脊柱狭窄症 (LSS) 的存在有关. 然而,与LSS疼痛和残疾有关的其他副脊髓肌肉关联仍然不清楚,限制了临床效用.
科学领域:
- 脊柱成像和诊断工作
- 肌肉骨研究的研究.
- 临床流行病学临床流行病学
背景情况:
- 越来越多的兴趣存在于将副脊柱肌肉特征与腰椎脊柱狭窄症 (LSS) 等脊柱疾病联系起来.
- 副脊髓肌肉形态/组成和LSS之间的确切关系仍然不太清楚.
- 本综述综合了有关这些关联的当前证据.
研究的目的:
- 系统地审查和综合有关LSS.相关的副脊髓肌肉形态和组成的证据.
- 检查与LSS存在,疼痛和残疾或功能相关的关联.
- 评估证据确定确定协会的确定性.
主要方法:
- 进行了系统审查,搜索了多个数据库 (EMBASE,PubMed等). ) 的情况.
- 选择了研究,提取了数据,并由两名独立审稿人评估了偏见风险.
- 使用GRADE考虑的叙事综合总结了证据.
主要成果:
- 多肌是最受研究的 (22项研究),其次是psoas (10项研究).
- 脂肪透和横截面积 (CSA) 是常见的现象型被检查.
- 中等确定性证据将增加的多脂肪透与LSS存在联系起来.
- 高确定性证据显示,多种类型的脂肪透与疼痛严重程度,或多种类型的CSA和LSS残疾之间没有联系.
- 其他关联,包括与勃起脊柱肌肉相关的关联,显示没有关联的中等确定性或仍未确定.
结论:
- 多种类型的脂肪透始终与LSS.的存在有关.
- 其他检查的与LSS (疼痛,残疾) 关联的副脊髓肌肉缺乏一致的证据或仍未确定.
- 准脊髓肌肉成像对LSS表型,预后和治疗的临床实用性需要进一步研究.
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