修改的袖口泄漏测试用于预测侵入性机械通风患者的再输管风险:多中心,单盲,随机对照试验
Xiao Tang1, Yan-Mei Gu2, Yuan Shi3
1Department of Respiratory and Critical Care Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China; Beijing Institute of Respiratory Medicine, Beijing, China; Beijing Engineering Research Center for Diagnosis and Treatment of Respiratory and Critical Care Medicine (Beijing Chao-Yang Hospital), Beijing, China; Beijing Key Laboratory of Respiratory and Pulmonary Circulation Disorders, Beijing, China.
修改后的袖口泄漏测试 (CLT) 可以更好地预测后管流器 (PES),但不会降低重新管率. 这种方法对于长期使用侵入性机械通风 (IMV) 的患者尤其有用.
科学领域:
- 关键护理医学 关键护理医学
- 呼吸系统疗法 呼吸系统疗法
- 麻醉学 麻醉学
背景情况:
- 袖口泄漏测试 (CLT) 对于评估口风险至关重要.
- 上呼吸道阻塞是输出管后的一个重要问题.
研究的目的:
- 将修改后的CLT方法与传统方法进行比较.
- 为了确定修改后的CLT是否改善了重新输管的预测.
主要方法:
- 未来的多中心随机对照试验涉及536名患者.
- 主要终点:在48小时内重新输管.
- 二级终点:术后风 (PES) 和侵入性机械通风 (IMV) 持续时间.
主要成果:
- 两组之间再输卵率没有差异.
- 修改后的CLT显示24小时内PES的发病率较高 (5.22%对1.49%).
- 修改后的CLT组的IMV持续时间更短 (137小时与159小时相比).
结论:
- 修改后的CLT可能会提高PES的预测,特别是在IMV>6天的患者中.
- 修改后的CLT并没有降低再化发生率或死亡率.
- 进一步的研究可能会完善CLT在输出管决策中的作用.
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