生命必需8和胆结石之间的关联:一个横截面研究
Yang Zhao1, Xuesong Liu2, Jingru Han2
1Department of Oncology, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province, China. zhaoyang7834@163.com.
Scientific reports
|February 8, 2025
概括
通过Life's Essential 8 (LE8) 改善心血管健康 (CVH) 显著降低了美国成年人的胆结石风险. 较高的LE8分数与患胆结石的可能性降低有关.
科学领域:
- 心血管健康 心血管健康
- 胃肠病学 胃肠病学
- 公共卫生 公共卫生
背景情况:
- 心血管健康 (CVH) 对于整体健康至关重要.
- 胆结石是一种常见的胃肠道疾病,对健康有重大影响.
- 生活必需品8 (LE8) 提供了CVH的全面衡量,包括行为和因素.
研究的目的:
- 调查生活必需品8 (LE8) 评分与美国成年人群中的胆结石患病率之间的关联.
- 为了确定更高的心血管健康水平是否有助于防止胆结石形成.
主要方法:
- 分析了来自2017-2020年国家健康和营养检查调查的5,024名美国成年人 (20岁以上) 的数据.
- 通过问卷评估胆结石的存在;CVH用LE8得分测量 (分类为低,中等,高).
- 使用加权后勤回归,受限立方线和分层分析来检查LE8-gallstone关系.
主要成果:
- 11.22%的参与者报告患有胆结石.
- 高CVH (LE8 ≥80) 与较低CVH (LE8 <50) (OR:0.41,95% CI:0.23-0.72) 相比,与胆结石风险降低59%有关.
- 观察到一种非线性关系,在年轻人 (<65岁),女性,非白人以及具有高等教育或已婚的人群中存在更强烈的关联.
结论:
- 较高的心血管健康,如LE8得分所示,与美国成年人胆结石风险降低显著相关.
- 在公共卫生倡议中,LE8为评估胆结石风险提供了有价值的工具.
- 进一步的研究可能会探索不同的人口群体之间这种关联背后的机制.
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