血红蛋白调解了"周末战士"身体活动模式和糖尿病视网膜病变之间的联系
Baohua Li1, Bobiao Ning2, Xinyue Hou1
1China Academy of Chinese Medical Sciences Eye Hospital, No.33 Lu-Gu Road, Shijingshan District 100040, Beijing, People's Republic of China.
参与周末战士 (WW) 或定期活跃 (RA) 身体活动 (PA) 模式可以显著降低糖尿病视网膜病变 (DR) 的风险. 血水平部分调解了这种保护作用,突出了成本有效的预防策略.
科学领域:
- 眼科和公共卫生.
- 运动生理学和慢性疾病预防
背景情况:
- 糖尿病视网膜病变 (DR) 是老年人视力丧失的主要原因,治疗选择有限.
- 确定DR的可修改风险因素对于有效的预防策略至关重要.
- 身体活动 (PA) 模式,包括"周末战士" (WW) 风格,是降低风险的潜在目标.
研究的目的:
- 调查美国成年人中战后体力活动 (PA) 模式与糖尿病视网膜病变 (DR) 风险之间的关联.
- 检查血红蛋白 (Hb) 水平在PA模式和DR风险之间的关系中的调解作用.
主要方法:
- 对国家代表性NHANES数据 (2007-2018) 的横截面分析.
- PA模式的分类:不活跃,不够活跃,WW和经常活跃 (RA).
- 多变量逻辑回归和调解分析,以评估DR风险和Hb水平的影响.
主要成果:
- 与不活动模式相比,WW和RAPA模式都与DR风险显著降低相关.
- 不活跃的PA模式成为DR的重要风险因素.
- 血水平显示了PA模式与DR风险之间的关联的显著部分调解 (5.95%) .
结论:
- 身体活动模式作为预防糖尿病视网膜病变的保护因素.
- 血红蛋白水平在身体活动和DR之间的保护性关联中起着调解作用.
- 这种WWPA模式代表了潜在的成本效益高的DR预防策略.
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