公共资助的通用药物计划与向儿童发放抗精神病和抗抑郁药物之间的关联
Sophie A Kitchen1, Tara Gomes1,2,3,4, Mina Tadrous1,3,5
1ICES, Toronto, Canada.
BMC pediatrics
|February 8, 2025
概括
安大略省的全民医疗计划 (OHIP+) 没有影响儿童抗抑郁药或抗精神病药物处方率. 政策变化,包括覆盖限制,与年轻人的药物发行趋势没有关联.
科学领域:
- 儿科药理学 儿科药理学
- 卫生政策分析 卫生政策分析
- 公共卫生研究 公共卫生研究
背景情况:
- 全球抗抑郁药和抗精神病药对儿童的处方增加.
- 对药物资助政策如何影响儿科处方实践的理解有限.
- 安大略省为儿童和青少年推出并随后修改了全民医疗保健计划 (OHIP+).
研究的目的:
- 调查安大略省OHIP+医疗保健政策变化与儿童抗抑郁药和抗精神病药的处方趋势之间的联系.
- 评估普遍药物覆盖和随后的覆盖限制对儿科精神药物药物发行的影响.
主要方法:
- 基于人口的研究分析了2014年9月至2020年2月为儿童 (≤18岁) 发行数据.
- 使用IQVIA地理处方监控数据库来发布信息.
- 采用自回归集成移动平均 (ARIMA) 模型来评估政策对发行率的影响.
主要成果:
- OHIP+的实施没有显示出与抗抑郁药或抗精神病药物发行率的变化有显著的关联.
- 随后的计划修订,将覆盖范围限制在没有私人保险的人身上,也与改变的发放趋势没有相关性.
- 所有观察到的变化的置信区间包括零,表明没有统计学意义上的影响.
结论:
- 在安大略省引入一项公共资助的医疗保健计划并没有影响儿童中抗抑郁药或抗精神病药的发行趋势.
- 旨在扩大药物覆盖范围的政策干预措施没有改变儿科人口中这些药物的既定处方模式.
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