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Updated: May 28, 2025

A "Plug-And-Display" Nanoparticle Vaccine Platform Based on Outer Membrane Vesicles Displaying SARS-CoV-2 Receptor-Binding Domain
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显示RBD的OMV纳米疫苗可以增强对SARS-CoV-2的免疫力

Rang Feng1,2, Ruo-Yi Xue1,3, Chang Liu1

  • 1National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University (Army Medical University), Chongqing, 400038, People's Republic of China.

Journal of nanobiotechnology
|February 8, 2025
PubMed
概括

携带SARS-CoV-2受体结合域 (RBD) 的外膜囊泡 (OMV) 被开发为纳米疫苗. 这种新型OMV-RBD疫苗有效地引起强烈的免疫反应并中和SARS-CoV-2,为COVID-19疫苗开发提供了一个有希望的替代方案.

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