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血红蛋白,白蛋白,淋巴细胞和血小板分数与危急病患者的短期死亡率之间的相关性
Chong Zhang1,2,3,4,5, Wenjin Peng1,2,3,4,5, Meng Ning1,2,3,4,5
1The Third Central Clinical College of Tianjin Medical University, Tianjin, 300170, China.
Journal of health, population, and nutrition
|February 8, 2025
概括
血红蛋白,白蛋白,淋巴细胞和血小板 (HALP) 评分可以预测重症患者的短期死亡率. 它还提高了序列器官衰竭评估 (SOFA) 评分的预测能力.
科学领域:
- 关键护理医学 关键护理医学
- 生物标志物 生物标志物
- 预测分析是一种预测分析.
背景情况:
- 血红蛋白,白蛋白,淋巴细胞和血小板 (HALP) 评分评估炎症和营养状况.
- 它在重症患者中的作用和增量预测价值尚未得到充分确立.
- 序列器官衰竭评估 (SOFA) 评分是评估器官功能障碍的一个关键工具.
研究的目的:
- 评估HALP评分对重症患者死亡率的预测值.
- 为了确定HALP得分是否提供超出SOFA得分的增量预测能力.
- 调查HALP得分与各种死亡结果之间的关联.
主要方法:
- 使用了密集护理医疗信息中心 (MIMIC-IV) 数据库 (2.2版本).
- 分析了20083名危急病患者的数据.
- 使用后勤回归和Cox比例危险模型来评估包括ICU死亡和28天死亡率在内的结果.
主要成果:
- 较低的HALP得分 (<3.56) 与显著更高的ICU死亡风险相关 (aOR: 1.41,95%CI: 1.25-1.59).
- 哈尔普得分显示了SOFA得分的增量预测能力 (∆AUC:0.009,p<0.001).
- 较低的HALP得分 (<3.2) 也预测了较高的28天死亡率 (aHR: 1.52,95% CI: 1.33-1.74).
结论:
- 哈尔普得分是重症患者短期死亡率的重要预测指标.
- 当HALP得分与SOFA得分相加时,它为预测短期死亡率提供了增量值.
- 研究结果支持HALP得分在重症监护机构的有用性.
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