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Updated: May 13, 2026

Chemotherapy-induced Vascular Toxicity - Real-time In vivo Imaging of Vessel Impairment
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在Cr(VI) 诱导的致癌过程中 Nrf2/cyclooxygenase 2 信号

Lei Zhao1, Yi-Fang Wang1, Andrea Adamcakova-Dodd2

  • 1Department of Pathology, University of Iowa, Iowa, IA 52242, USA; Department of Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA.

Ecotoxicology and environmental safety
|February 9, 2025
PubMed
概括

六价 (Cr(VI)) 暴露会导致肺癌,其中环氧化酶-2 (COX-2) 作为基因. 这项研究揭示了Nrf2对COX-2进行上调,而miR-379则对其进行下调,影响CrVI诱导的肺癌发生.

关键词:
在COX-2中,COX-2是最常见的.致癌的发生是致癌的产生.这就是Cr (VI) 的意思.Nrf2 没有任何问题.这里是 miR-37979 的位置.

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