中国水资源中潜在有毒元素 (PTEs) 的度和人类健康风险:系统审查和元分析
Xiaomei Hui1, Anhui Li2, Sheng Chang3
1Shanxi Vocational University of Engineering Science and Technology, Shanxi, China; State Environmental Protection Key Laboratory of Drinking Water Source Protection, Chinese Research Academy of Environmental Sciences, Beijing, China.
Ecotoxicology and environmental safety
|February 9, 2025
概括
在中国,长期暴露于潜在有毒元素 (PTEs).
科学领域:
- 环境科学 环境科学
- 公共卫生 公共卫生
- 毒理学 毒理学 毒理学
背景情况:
- 长期暴露于潜在有毒元素 (PTEs) 构成显著的致癌和非致癌健康风险.
- 水资源是人类暴露于PTE的主要途径.
研究的目的:
- 进行对中国水资源中PTE度的元分析.
- 评估与成人男性和女性饮用水中的PTE相关的人类健康风险.
- 确定关键的PTE及其导致健康风险的来源.
主要方法:
- 从2005年到2024年,对国际数据库 (Web of Science,Scopus,PubMed,Embase,Google Scholar) 进行系统的文献搜索.
- 使用随机效应模型对PTE度 (As,Cd,Pb,Hg,Ni,Cu) 的元分析.
- 使用摄入和皮肤接触途径的目标危险系数 (THQ) 和总致癌风险 (TCR) 进行人类健康风险评估.
主要成果:
- (As) 呈现了最高的聚合度和超出标准限值的研究比例最高.
- 和 (Cd) 对男性和女性构成最高的致癌风险.
- 也呈现了最高的非致癌风险 (THQ) 两性.
结论:
- 是中国水资源中令人担忧的关键PTE,具有显著的致癌和非致癌风险.
- 建议进行持续的监测,并采用新的方法来控制释放到水中.
- 公共卫生干预措施应侧重于通过饮用水减轻接触和的风险.
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