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Updated: May 28, 2025

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从CD19 CAR-T细胞疗法转录的单细胞转录基因分析骨髓系的进化 CD19 CAR-T细胞治疗

Yajuan Cui1,2, Peilong Wang3,4, Hongkai Zhu3,4

  • 1Department of Hematology, The Second Xiangya Hospital, Central South University, Changsha, China, cuiyajuan@csu.edu.cn.

Pathobiology : journal of immunopathology, molecular and cellular biology
|February 9, 2025
PubMed
概括

在CAR-T治疗期间,一种罕见的复发性急性B-淋巴细胞白血病转变为急性髓性白血病的罕见病例突出了潜在的机制. 这种进化涉及由ANXA1-FPR1/2轴驱动的骨髓系繁殖和血液造血干细胞中的6q删除.

关键词:
急性骨髓性白血病 (AML) 是一种急性骨髓性白血病.CD19导向的仿真抗原受体-T细胞受体.单细胞转录基因分析

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