线性增长促进干预对24个月儿童过度营养的影响:随机对照试验
Rukman Manapurath1, Ranadip Chowdhury2, Sunita Taneja2
1Centre for International Health, University of Bergen, Norway; Society for Applied Studies, New Delhi, India.
The American journal of clinical nutrition
|February 9, 2025
概括
在最初的1000天内进行全面干预,改善了儿童的生长,而不会增加超重或肥胖. 这些"双重任务"行动解决了低收入和中等收入国家 (LMICs) 的营养不良问题.
科学领域:
- 全球健康 全球健康
- 营养科学 营养科学
- 儿科健康 儿科健康
背景情况:
- 儿童营养不良 (营养不良和营养过剩) 是低收入和中等收入国家 (LMICs) 的一个关键问题.
- 针对营养不良的早期干预措施可能无意中增加肥胖风险.
- 以前的研究表明,在最初的1000天内进行干预可以减少发育迟缓,但对身体组成和超重的影响尚不清楚.
研究的目的:
- 评估旨在预防头1000天的发育迟缓的干预措施对1个月的婴儿身体组成的影响.
- 评估这些干预措施对24个月龄的儿童超重和/或肥胖的影响.
主要方法:
- 在1个月后,使用乳稀释剂分析婴儿的身体组成.
- 儿童超重/肥胖患病率在24个月时使用Body Mass Index-for-Age Z (BMIz) 评分>+2 SD确定.
- 与常规护理相比,干预组包括先孕,怀孕和幼儿,或怀孕和幼儿,与常规护理相比.
主要成果:
- 与常规护理相比,干预组的BMIz得分较高,但超重/肥胖的患病率仍然很低 (0.0-1.3%).
- 怀孕干预显著增加了新生儿的无脂肪质量 (增加0.1公斤).
- 没有观察到新生儿脂肪质量的显著变化.
结论:
- 从怀孕前到幼儿时代的综合干预措施可以增强线性生长,而不会导致24个月的超重/肥胖.
- 这些干预措施与世卫组织的"双重营养行动"一致,通过改善线性和沉思性生长.
- 这些发现对于面临营养不良和儿童肥胖率上升的双重负担的LMICs至关重要.
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