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人类免疫缺陷病毒损害了对瘤新皮质的免疫反应,而不会改变NSCLC中的突变概况

Baptiste Abbar1, Karim Labreche2, Jacques Cadranel3

  • 1Centre d'Immunologie et des Maladies Infectieuses (CIMI-Paris), Institut national de la santé et de la recherche médicale (INSERM) U1135, CNRS ERL8255, Sorbonne Université, Paris, France; Department of Medical Oncology, Assistance Publique - Hôpitaux de Paris (AP-HP), Pitié-Salpêtrière Hospital, Institut Universitaire de Cancérologie, Sorbonne Université, Paris, France.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
|February 9, 2025
PubMed
概括

艾滋病毒感染会损害非小细胞肺癌 (NSCLC) 患者的抗瘤免疫力. 尽管瘤形状相似,但艾滋病毒感染者 (PLWHIV) 显示T细胞反应减少,特别是对MHC I类新表位细胞,影响免疫治疗的有效性.

关键词:
艾滋病病毒 艾滋病病毒 艾滋病病毒分子形状的分子形状.在NSCLCLC中,我们可以看到.瘤微环境是一个微环境.瘤的新位体.

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