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Updated: May 28, 2025

Identification of Kinase-substrate Pairs Using High Throughput Screening
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Identification of Kinase-substrate Pairs Using High Throughput Screening

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识别受体激酶基质 使用 8000 个类激酶客户端库,为保存的酸化站点进行丰富

Daewon Kim1, Gabriel Lemes Jorge2, Chunhui Xu3

  • 1Division of Plant Science & Technology, C.S. Bond Life Sciences Center, University of Missouri, Columbia, Missouri, USA.

Molecular & cellular proteomics : MCP
|February 9, 2025
PubMed
概括

激酶客户端 (KiC) 试验识别了激酶的蛋白质基质. 一个扩展的8k库成功地确定了P2K1激酶的新基质,揭示了新的植物信号通路.

关键词:
阿拉比多普西斯塔利亚纳.激酶-客户端测试试验这就是P2K1的原因.类酸是一种酸.类似受体激酶的受体

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Receptor Tyrosine Kinases01:26

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Receptor tyrosine kinases or RTKs are membrane-bound receptors that phosphorylate specific tyrosine on protein substrates. RTKs regulate cellular growth, differentiation, survival, and migration. They contain an extracellular ligand binding domain, a transmembrane domain, and a cytosolic tail with intrinsic kinase activity. Several extracellular signaling molecules activate RTKs in one or more ways and relay the signal downstream. Ligands such as platelet-derived growth factor (PDGF) or...
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