综述了肠-大脑相互作用障碍的成像最近的发展情况
Noriaki Manabe1, Masafumi Wada2, Tsutomu Takeda3,4
1Division of Endoscopy and Ultrasonography, Department of Clinical Pathology and Laboratory Medicine, Kawasaki Medical School, 2-6-1 Nakasange, Kita-ku, Okayama 700-8505, Japan.
肠-大脑相互作用障碍 (DGBI) 涉及遗传学和肠道微生物群等因素. 正在开发先进的成像技术,以评估DGBI患者的上部胃肠道运动问题.
科学领域:
- 胃肠病学和神经胃肠病学
- 生物医学成像技术 生物医学成像技术
- 微生物组研究 微生物组研究
背景情况:
- 肠-大脑相互作用障碍 (DGBI) 与遗传,环境,微生物和炎症因素有关.
- 胃肠道运动障碍是DGBI发展和表现的一个关键因素.
- 目前对DGBI运动异常的评估很大程度上依赖于运动测量.
研究的目的:
- 审查与DGBI相关的上部胃肠道的功能变化.
- 描述评估食道和胃运动功能障碍的新兴成像方法.
- 突出高级成像在DGBI研究和临床实践中的潜力.
主要方法:
- 综合性文献综述,重点关注DGBI病理生理学和上部消化道功能.
- 分析当前和正在发展的成像技术,以评估食道和胃机动性.
- 探索胃肠道运动测量在DGBI管理中的作用.
主要成果:
- DGBI的发展是多因素的,涉及遗传学,早期生活,微生物群和炎症.
- 胃肠道运动障碍在DGBI中扮演着双重角色,既是DGBI的原因,也是表型.
- 新的成像模式显示出对DGBI上部胃肠道运动异常的评估有希望.
结论:
- 胃肠道运动测量对于那些对一线治疗没有反应的DGBI患者至关重要.
- 先进的成像技术为了解DGBI病理生理学提供了新的途径.
- 这些成像技术的进步为未来的DGBI研究和临床应用带来了巨大的潜力.
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