从生理学的角度来看,远部胃切除术后的胃排空:加速还是延迟?
Chikashi Shibata1, Kentaro Sawada1, Atsushi Mitamura1
1Department of Gastroenterolgic Surgery, Tohoku Medical and Pharmaceutical University, 1-12-1 Fukumuro, Miyaginoku, Sendai, Miyagi 983-8512, Japan.
概括
远距离胃切除术后的胃排空速度较快,最初用于液体和固体. 然而,固体食物的排空时间延迟到餐后60分钟,这与典型的假设相矛盾.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 消化系统生理学 消化系统生理学
背景情况:
- 远程胃切除术是胃癌的常见手术.
- 手术后的胃排空通常被认为是加速的.
- 对食品残留物的临床观察表明,清空延迟,造成了差异.
研究的目的:
- 为了研究远端胃切除术后液体和固体的明显胃排空模式.
- 为了协调关于手术后胃排空速度的相互矛盾的观察.
主要方法:
- 系统审查研究评估胃空化使用scintigraphy在人类.
- 分析影响远部胃切除术后胃空化的生理变化.
主要成果:
- 胃液的排泄在距离胃切除术后持续加快.
- 固体的初始排空也加快了,但在60分钟后发生了显著的保留.
- 延迟固体胃排空与胃残留物中观察到的食物残留物相关.
结论:
- 距离胃切除术后的胃排空显示了一种双重模式:在液体和初始固体中加速,但在固体中延迟.
- 延迟固体排空是胃残留食物保留的一个关键因素.
- 目前对加速胃排空的理解需要改进,以包括延迟的固体排空.
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