在社区获得的肺炎的住院患者中,副肺喷液是VTE的危险因素:一项回顾性队列研究
Xin-Yu Shi1, Yi-Xiao Zhang1, Feng-Shuang Yi1
1Department of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine and Beijing Chao- Yang Hospital, Capital Medical University, 8 Gongti Nanlu, Chao-Yang District, Beijing, 100020, China.
副肺流 (PPE) 是静脉血栓塞栓症 (VTE) 的独立风险因素,用于社区获得性肺炎 (CAP) 的住院患者. 带有个人防护设备的患者表现出高度炎症,需要改进VTE预防和治疗策略.
科学领域:
- 肺部医学 肺部医学
- 心血管医学 心血管医学
- 关键护理医学 关键护理医学
背景情况:
- 静脉血栓塞栓症 (VTE) 构成一个重大的全球健康风险.
- 社区获得性肺炎 (CAP) 经常导致住院治疗.
- 肺炎的并发症 - - 副肺肺流 (PPE) 之前没有被研究为VTE风险因素.
研究的目的:
- 为了调查是否 parapneumonic 肺流 (PPE) 是静脉血栓塞栓症 (VTE) 的风险因素在住院患者诊断为社区获得的肺炎 (CAP).
主要方法:
- 对703名被诊断患有CAP的住院患者进行了回顾性队列研究.
- 用单变量和多变量逻辑回归分析临床和实验室数据.
- 亚组分析以评估个人防护设备和VTE之间的相关性.
主要成果:
- 在703名住院患者中,有73名患有静脉瘤.
- 个人防护设备,年龄,性别,D-二次数和肺炎严重程度指数是重要的静脉瘤风险因素.
- 患有PPE的患者表现出炎症标志物 (中性粒细胞,C反应蛋白,D-二次体) 和凝血指标 (血小板,前血时间) 的升高.
结论:
- 副肺性流 (PPE) 是住院CAP患者中VTE的一个独立风险因素.
- 在使用PPE的患者中观察到较高的炎症反应.
- 临床医生应加强住院CAP患者的VTE监测和管理.
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