基于试验的BrainACT研究的经济评估:接受和承诺治疗获得脑损伤后的焦虑和/或抑郁症状
Sander Osstyn1, Johanne Rauwenhoff2,3,4, Ron Handels1
1Department of Psychiatry and Neuropsychology and Alzheimer Center Limburg, School for Mental Health and Neuroscience (MHeNS), Maastricht University, Maastricht, The Netherlands.
International journal of technology assessment in health care
|February 10, 2025
概括
在获得脑损伤的患者中,BrainACT疗法显著降低了焦虑和抑郁. 这种干预措施显示出作为一种具有成本效益的治疗方法的希望,尽管需要进一步的研究才能广泛实施.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 卫生经济学 卫生经济学
背景情况:
- 获得性脑损伤 (ABI) 经常导致焦虑和抑郁症状.
- BrainACT是一种适应的接受和承诺疗法 (ACT),专为ABI患者设计.
- 这项研究评估了BrainACT与对照干预 (精神教育和放松) 相比.
研究的目的:
- 与对照治疗相比,对BrainACT进行健康经济评估.
- 评估BrainACT对ABI患者的成本效益和成本效益.
- 为了分析焦虑和抑郁症症状在1年时间内的变化.
主要方法:
- 一个多中心随机对照试验,在荷兰有72名参与者.
- 社会视角的成本效益和成本效益分析.
- 收集了有关成本,质量调整后寿命年 (QALYs) 和医院焦虑和抑郁量表 (HADS) 评分的数据.
- 利用启动,场景和子组分析以获得稳定性.
主要成果:
- BrainACT的结果是,总成本没有显著降低 (4,881欧元).
- 显著减少焦虑/抑郁症状 (HADS评分减少3.2).
- 对BrainACT的QALY没有显著降低 (-0.008).
- 在5万欧元/QALY门下,成本效益的概率为86%.
结论:
- 在ABI后,BrainACT为管理焦虑/抑郁症提供了一个潜在的更具成本效益的选择.
- 该干预措施是荷兰临床环境的一个有希望的补充.
- 建议进行进一步的研究和临床实施,并进行监测.
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