在尿路透镜检查前尿液培养中混合植物的患者感染风险
Joshua K Kim1, Ezra J Margolin1, David L Barquin1
1Department of Urologic Surgery, Duke University School of Medicine, Durham, North Carolina, United States.
Journal of endourology
|February 10, 2025
概括
在接受尿路透镜检查的患者手术前的混合植物尿液培养不会增加感染风险. 对混合动植物的常规抗生素使用可能无法预防手术后感染,这表明需要重新评估当前的指导方针.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 传染性疾病 传染性疾病
- 医学微生物学 医学微生物学
背景情况:
- 尿培养指导在内分泌外科手术前使用抗生素.
- 在手术前的尿液培养中混合植物的意义尚不清楚.
- 这项研究调查了经过尿路透镜检查的混合植物尿液培养患者的感染结果.
研究的目的:
- 确定手术前尿液培养物中混合植物的临床意义.
- 为了比较混合植物,阴性和阳性尿液培养的患者的术后感染率.
- 评估手术前抗生素在患有混合植物尿液培养的患者中的有效性.
主要方法:
- 成年患者进行激光光透术的回顾性队列研究 (2014年1月 - 2024年6月).
- 患者被分为混合植物,阴性或阳性手术前尿液培养组.
- 使用逻辑回归来比较30天后手术后的尿路感染 (UTI) 率.
主要成果:
- 包括5166名患者:2139种混合植物,1525种负,1502种阳性培养.
- 手术后感染率:8% (混合植物),6% (阴性),16% (阳性).
- 混合植物和消极培养显示出相似的感染风险;积极的培养显著增加了风险 (OR=1.95). 在混合植物病例中,手术前的抗生素没有减少感染.
结论:
- 手术前的混合植物尿液培养与尿管镜检查后的术后感染风险增加无关.
- 目前在混合植物群中常规使用抗生素的做法可能没有好处.
- 需要进行进一步的研究,以优化内分泌手术中的抗生素策略.
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