作为新兴病原体的Actinomyces物种:临床感染和微生物学影响的观察性研究
Abraham A Ayantunde1, Joanne Kiang2, Nadeem S Raja3
1Department of General Surgery, Southend University Hospital, Southend-on-Sea, GBR.
Cureus
|February 10, 2025
概括
目前,Actinomyces感染的数量正在上升,通常以脂质囊或柱状的形式出现. 由于越来越多的报告和治疗挑战,建议对Actinomyces流行病学和耐药性的监测.
科学领域:
- 医学微生物学 医学微生物学
- 传染性疾病 传染性疾病
背景情况:
- Actinomyces物种是人类通道的共同体,但当组织完整性受到损害时,可能会导致罕见的感染.
- 与Actinomyces物种相关的感染正在增加,这给治疗带来了挑战.
研究的目的:
- 评估Actinomyces物种相关感染的模式,表现和风险因素.
- 分析孤立的Actinomyces物种的抗生素敏感性.
主要方法:
- 在2016年7月至2021年4月期间,从各种临床样本 (血液,组织,液体,骨,拭子) 中分离出Actinomyces的145名患者的回顾性评估.
- 根据EUCAST指南进行的抗生素敏感性测试.
- 电子医疗记录被检查了人口统计和临床病理学数据.
主要成果:
- 最常见的表现是受感染的脂质囊 (25.5%) 和柱状 (13.8%).
- Actinomyces物种经常从擦拭物 (78) 和 (32) 中分离出来.
- 最常见的物种是Actinomyces neuii (24.8%),Actinomyces turicensis (22.8%),以及Actinomyces europaeus (13.8%),这些都是最常见的物种. 在57.2%的样本中观察到混合微生物生长.
结论:
- 越来越多地报告了Actinomyces物种感染,可能是由于改良的培养技术.
- 建议对与Actinomyces物种相关的感染进行流行病学和耐药性监测.
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