监管合成新型精神活性物质的挑战:从日本对六大麻 (hexahydrocannabihexol) 的通用规划中吸取教训
Natsuki Yokoyama1,2, Tatsuki Ikejiri1, Hayase Hakariya1,3,4
1Laboratory for Human Nature, Cultures and Medicine, Kyoto, Japan.
JMA journal
|February 10, 2025
概括
由于恶心和头等健康风险,日本已经禁止合成大麻素Hexahydrocannabihexol (HHCH). 这一行动解决了新兴精神活性物质对公众健康的日益关注.
科学领域:
- 药理学 药理学是指药理学的学科.
- 毒理学 毒理学 毒理学
- 公共卫生政策 公共卫生政策
背景情况:
- 合成大麻素,如六大麻醇 (HHCH),构成新出现的健康风险,包括中枢神经系统的影响,如恶心和头.
- 日本卫生,劳工和福利部 (MHLW) 历史上一直在调整药物法规,以解决现有法律未涵盖的新型精神活性物质 (NPS).
- 越来越多的NPS患病率导致中毒病例的增加,促使监管机构实施通用调度系统.
研究的目的:
- 报告日本关于合成大麻素六大麻醇 (HHCH) 的监管行动.
- 突出HHCH和类似新兴精神活性物质对公共健康的影响.
- 讨论监管合成大麻素的挑战和局限性.
主要方法:
- 审查日本MHLW于2023年12月2日宣布的监管条例.
- 对HHCH的化学结构和报告的不良影响的分析.
- 检查日本不断发展的药物控制战略及其有效性.
主要成果:
- 日本已经实施了一项条例,以规范HHCH的拥有,消费和分发,但医疗用途除外.
- HHCH与四大麻素的结构相似性被认为是其中枢神经系统不良影响的原因.
- 尽管此前有过监管工作,但与设计药物相关的逮捕事件却有所回升,部分原因是网上可访问性增加.
结论:
- 高化制造商的持续存在表明现有监管框架的局限性.
- 提高健康素养和社会责任对于减轻与新兴精神活性物质相关的公共卫生风险至关重要.
- 在处理合成大麻素时,未来的监管框架必须优先考虑公共卫生方面的考虑,而不是经济利益.
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