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胃肠道神经瘤的临床病理特征和治疗方法
Peng-Cheng Zhang1, Shu-Hui Wang2, Jun Li3
1Department of Gastroenterology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, Zhejiang Province, China.
World journal of gastroenterology
|February 10, 2025
概括
胃肠道神经瘤 (GIS) 是一种罕见的瘤. 准确的手术前诊断是具有挑战性的,但内镜超声波引导的细针吸入有助于检测,内镜治疗对于较小的病变是有效的.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 病理学 病理学 病理学
背景情况:
- 胃肠道神经瘤 (GIS) 是一种罕见的神经性瘤,起源于斯万细胞.
- 有限的研究和特定地点的研究突出了诊断和治疗方面的挑战.
研究的目的:
- 综合分析GIS的临床特征,病理,治疗结果,并发症和预后.
- 为了提高诊断准确度和治疗策略的胃肠道神经瘤.
主要方法:
- 从2007年到2024年,对229名被诊断患有GIS的患者进行了回顾性分析.
- 包括人口统计数据,内镜/成像检测结果,治疗,病理和随访.
- 使用内镜超声波引导细针吸收与免疫组织化学 (S100,SOX-10) 进行诊断.
主要成果:
- 大多数GIS (76.9%) 是胃的,平均尺寸为2.75厘米.
- 在手术前误诊为胃肠道 stromal 瘤是常见的.
- 对较小的瘤进行内镜切除和对较大的瘤进行外科切除,均取得了良好的结果.
结论:
- 准确的手术前诊断GIS仍然具有挑战性,但至关重要.
- 带有免疫组织化学的内镜超声波引导细针吸收改善了诊断的准确性.
- 内镜治疗是GIS的最小侵入性和有效的治疗选择.
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