粘膜切除-内镜下粘膜挖掘用于胃下粘膜瘤:一项回顾性研究 (附视频)
Wei Wei1, Xiaolong Zheng1, Yongli Ye1
1Department of Gastroenterology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Frontiers in oncology
|February 10, 2025
概括
粘膜切除-内镜下粘膜挖掘 (MSR-ESE) 与内镜下粘膜挖掘 (ESE) 相比,在胃下粘膜瘤方面提供了更好的结果. MSR-ESE导致程序缩短,成本降低,并发症减少.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 最少侵入性手术的方法
背景情况:
- 胃下粘膜瘤 (SMTs) 是一个常见的临床挑战.
- 内镜下粘膜挖掘 (ESE) 和粘膜陷切除-内镜下粘膜挖掘 (MSR-ESE) 是SMT管理的新兴技术.
研究的目的:
- 为了比较ESE与MSR-ESE的临床结果,用于治疗胃下粘膜瘤.
- 在回顾性队列中评估MSR-ESE的安全性和有效性.
主要方法:
- 对180名接受ESE或MSR-ESE的SMT患者的回顾性分析.
- 操作时间,手术内并发症,术后康复和成本的比较.
- 使用倾向得分匹配 (PSM) 和多变量逻辑回归.
主要成果:
- 在MSR-ESE和ESE组之间,术后使用抗生素,禁食时间或手术内穿孔没有显著差异 (P>0.05).
- MSR-ESE组显示显著缩短了手术时间,住院时间和成本 (P<0.05).
- MSR-ESE与手术后腹膜炎的发病率降低有关 (P<0.05).
- 手术时间被确定为手术内穿孔的独立风险因素 (P=0.007).
结论:
- MSR-ESE是一种安全有效的替代ESE用于胃SMTs.
- MSR-ESE提供了优势,包括缩短手术时间,降低成本和减少术后并发症.
- 优化操作时间可能进一步降低ESE程序中的穿孔风险.
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