原发性淋巴瘤发生在帕杰特病中,发生在患有原发性副甲状腺炎症的患者身上
Mercedes De La Fuente1, Marina Arroyo2, Ana S Collado3
1Division of Internal Medicine, Hospital Universitario Marqués de Valdecilla, Santander, Spain.
European journal of case reports in internal medicine
|February 10, 2025
概括
这份病例报告详细介绍了一例极为罕见的56岁男子被诊断出非霍奇金病的情况.
科学领域:
- 骨疾病和瘤学
- 内分泌学和恶性病变
背景情况:
- 帕杰特骨疾病 (PDB) 涉及异常的骨重塑.
- 在PDB中恶性转变通常呈现为骨髓瘤,淋巴瘤是非常罕见的.
- 在PDB和原发性甲状腺功能障碍症 (PHPT) 之间的联系是有争议的,与已确定的与二次性甲状腺功能障碍症的关联不同.
研究的目的:
- 报告一个独特的病例,同时存在帕杰特骨病,非霍奇金淋巴瘤和原发性副甲状腺功能障碍.
- 为了突出一级淋巴瘤在页形骨中发生的罕见情况.
- 为了强调PDB与PHPT的不同寻常的关联.
主要方法:
- 一个56岁的男性患者的病例介绍.
- 诊断工作包括骨活检.
- 对PDB,NHL和PHPT协会的现有文献的审查.
主要成果:
- 不霍奇金淋巴瘤 (NHL) 的诊断发生在页状骨中,通过活检得到证实.
- 该患者还被诊断出患有原发性副甲状腺功能障碍症 (PHPT).
- 这是第一个报告的病例,这三个条件 (PDB,NHL,PHPT) 在一个病人.
结论:
- 帕杰特骨疾病中的原发性淋巴瘤是一种极其罕见的并发症.
- 在一个患者中,PDB,NHL和PHPT的共存是前所未有的.
- 需要进一步的研究来阐明潜在的分子机制,将这三种不同的骨病理联系起来.
更多相关视频
07:12Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
Published on: August 17, 2022
3.3K
07:13Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation
Published on: March 14, 2017
14.5K
相关概念视频
The Parathyroid Glands
1.8K
The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
1.8K
Hormones and Bone Tissue
2.6K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
2.6K
Skeleton and Calcium Homeostasis
4.4K
Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
4.4K
