在2型糖尿病患者中,失脂症的频率和模式及其与其他危险因素的关联
Alia Ali Muhammad1, Manal Afzaal2, Mehak Joher Khan3
1Alia Ali Muhammad, FCPS Assistant Professor, Department of Medicine, Shaikh Zayed Postgraduate Medical Institute, Lahore, Pakistan.
2型糖尿病患者患有非常高的脂质失调症,特别是吸烟者,血糖失控者 (HbA1c) 或肥胖者. 早期查和治疗失脂血症对于降低心血管疾病风险至关重要.
科学领域:
- 内分泌学 在内分泌学.
- 心脏病学 心脏病学
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 脱脂症是2型糖尿病的一个重要并发症.
- 鉴定糖尿病患者与失脂症相关的危险因素对于预防策略至关重要.
研究的目的:
- 为了确定2型糖尿病患者的脱脂症的频率和模式.
- 为了研究失脂症与吸烟,血糖控制和肥胖等其他危险因素之间的关联.
主要方法:
- 进行了一项涉及212名2型糖尿病患者的横截面研究.
- 评估了禁食脂质样本,体重指数 (BMI),HbA1c和吸烟状况.
- 排除标准包括服用降脂药物或患有失脂血的二次原因的患者.
主要成果:
- 几乎所有的参与者 (96.6%) 呈现出血脂不良.
- 失脂症与吸烟,不受控制的HbA1c和肥胖症有显著的积极关联 (p < 0.001).
结论:
- 在2型糖尿病患者,特别是吸烟者,血糖控制不佳者以及超重/肥胖者中,缺脂症的患病率非常高.
- 早期查,改变生活方式和治疗失脂症可以减轻心血管疾病 (CVD) 的风险.
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