不同的儿科药物对RMGIC的影响:一项比较研究
Ahtesham A Qurishi1, Mohammed S Al Dira2, Amal H Sholan3
1Department of Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Jizan University, Jazan, Saudi Arabia.
Journal of pharmacy & bioallied sciences
|February 10, 2025
概括
儿科药物可能会损害在牙科中使用的树脂修饰玻璃离子体水泥 (RMGIC). 抗咳糖显著降低RMGIC微硬度,增加表面粗度,影响牙修复的耐用性.
科学领域:
- 牙科材料科学 牙科材料科学
- 儿科牙科 儿科牙科
- 生物材料 相互作用 相互作用
背景情况:
- 树脂修饰玻璃离子体水泥 (RMGIC) 是儿童牙科中常见的牙科修复材料.
- 经常使用的儿科药物和RMGIC之间的相互作用尚不清楚.
- 药物对RMGIC的潜在降解可能会危及牙修复的寿命.
研究的目的:
- 评估常见儿科药物对RMGIC物理性质的影响.
- 确定哪些类型的儿科药物对RMGIC构成最大风险.
- 为儿童修复牙科的材料选择和临床实践提供见解.
主要方法:
- 准备了60个RMGIC标本,并分为五组.
- 群体被浸泡在抗生素糖,抗发烧糖,维生素糖,抗咳糖或蒸水 (控制) 中长达14天.
- 浸泡前后测量了微硬度和表面粗度,并使用ANOVA和Tukey测试进行了统计分析.
主要成果:
- 所有测试的儿科药物都显著改变了RMGIC属性.
- 抗咳糖显示出最明显的负面影响,微硬度降低了高达18.40%,表面粗度增加了高达21.40%.
- 对照组 (蒸水) 没有显著变化,表明药物诱导的影响.
结论:
- 常见的儿科药物,特别是酸性配方,如抗咳糖,可能会损害RMGIC的耐用性.
- 这些发现突出了进一步研究开发更耐药的牙科材料或为儿科修复提供保护策略的需要.
- 临床医生应考虑液体药物对儿童RMGIC恢复寿命的潜在影响.
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