对抗生素处方的审计:在第三级护理公共医院进行抗生素管理预实施研究
Jowhara Cassim1, Sabiha Y Essack1,2, Sarentha Chetty1
1Discipline of Pharmaceutical Sciences, School of Health Sciences, University of KwaZulu-Natal, Westville Campus, Durban 4041, South Africa.
JAC-antimicrobial resistance
|February 10, 2025
概括
这次审计揭示了公共医院抗生素处方的重大问题,其中三分之二的处方不符合关键过程措施. 这些发现强调了对抗微生物药物管理计划的必要性,以改善抗生素的使用.
科学领域:
- 医学科学 医学科学 医学科学
- 临床药房 临床药房
- 传染性疾病 传染性疾病
背景情况:
- 抗微生物耐药性是一个日益增长的全球健康威胁.
- 适当的抗生素处方对于患者的治疗结果和抗药性制至关重要.
- 高级医院需要强大的抗菌药物管理计划.
研究的目的:
- 审计一家三级公立医院的抗生素处方实践.
- 在实施抗菌药物管理计划之前,确定需要改进的领域.
主要方法:
- 从2020年4月到6月,对380名患者的病历进行了回顾性审计.
- 评估过程措施,包括处方前培养,治疗持续时间,降级和同时使用抗生素.
- 使用 Stata (17 版) 的统计分析.
主要成果:
- 三分之二的抗生素处方显示不符合至少一个工艺措施.
- 观察到过长的治疗时间 (3.16%),缺乏缓解 (4.74%) 和有限的亲肠口服转换 (3.16%).
- 还注意到冗余的抗生素覆盖率 (36.05%) 和不遵守敏感性结果 (25.79%).
结论:
- 在受审计的人群中发现了不适当的抗生素处方.
- 该研究强调了实施抗微生物管理干预措施的必要性.
- 流程和结果措施对于有效的抗微生物药物管理至关重要.
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