围和直肠神经招募顺序在尾神经刺激器植入手术期间有所不同
Po-Ju Chen1,2, Amador C Lagunas1,2, Vanessa Soriano2,3
1Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
Neurourology and urodynamics
|February 10, 2025
概括
乳神经刺激 (PNS) 可以在直肠神经之前激活围神经,为盆腔疼痛提供新的见解,并消除功能障碍治疗. 电极的放置可能会影响尿道反应和患者的结果.
科学领域:
- 神经学 神经学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 盆腔健康 盆腔健康
背景情况:
- 乳神经刺激 (PNS) 是一种新兴的治疗方法,用于治疗盆腔疼痛和排泄功能障碍.
- 尾神经有直肠和周围的分支,但在手术期间通常只监测直肠分支.
- 了解神经招募顺序对于优化PNS治疗至关重要.
研究的目的:
- 为了调查在PNS期间的手术内神经神经招募命令.
- 为了将神经招募与尿道压力变化和患者报告的结果相关联.
- 为了提高PNS有效性,为外科置提供信息.
主要方法:
- 收集了13名接受PNS植入的患者的手术内数据.
- 在PNS期间使用多传感器导管测量尿道压力.
- 对比尿道压力变化和外部关节 (EAS) 电肌图,以确定神经招募顺序.
- 进行骨盆疼痛,膀,肠道和性功能的术前和术后调查.
主要成果:
- 神经招募顺序各不相同,7名患者首先显示直肠招募,4名患者首先显示周周招募,2名患者混合招募.
- 随着刺激强度的增加,观察到显著的尿道压力变化.
- 患者报告骨盆疼痛和膀功能显著改善 (p < 0.04).
- 在神经招募顺序和症状改善之间没有发现相关性.
结论:
- 精髓神经刺激可以在直肠神经之前招募周围神经.
- 个别的电极可能会引起不同的尿道反应.
- 这些发现提供了关于骨盆神经激活的见解,并指导了未来的PNS系统配置.
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