关于辐射视网膜病变的诊断和管理的最新情况
Eric A Lovett1, Jason Fan2, Basil K Williams2
1Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York.
Current opinion in ophthalmology
|February 10, 2025
概括
放射性视网膜病变,是放射治疗对视力构成的威胁,通过新的成像更好地检测到. 早期检测和个性化治疗,包括抗VEGF药物,改善了结果.
科学领域:
- 眼科医生 眼科 眼科
- 辐射瘤学 辐射瘤学
- 医疗成像医学成像
背景情况:
- 辐射视网膜病变是放射治疗的严重并发症,影响视力.
- 了解其发生率,危险因素和病理生理学对于患者护理至关重要.
研究的目的:
- 审查辐射视网膜病变的最新进展.
- 专注于发生率,危险因素,病理生理学,诊断成像,预防和治疗.
主要方法:
- 关于辐射视网膜病变的当前文献的综述.
- 对诊断成像技术的进展进行分析 (OCTA,UWFA).
- 评估预防和治疗策略,包括抗VEGF药物和皮质类固醇.
主要成果:
- 发病率与辐射剂量,分量和患者因素 (糖尿病,高血压) 有关.
- 先进的成像 (OCTA,UWFA) 提高了亚临床变化的早期检测.
- 使用抗VEGF药物的预防和抗VEGF/皮质类固醇等治疗方法有希望,但结果各不相同,需要个性化的方法.
结论:
- 辐射视网膜病变是一个重要的眼科挑战.
- 通过先进的成像和定制干预措施的早期检测是视觉结果的关键.
- 需要进一步研究新的治疗方法,并减少疾病的负担.
相关概念视频
Glaucoma: Overview
1.7K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.7K
Open Angle Glaucoma: Treatment
1.1K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.1K
Angle Closure Glaucoma: Treatment
1.6K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.6K
Photoreceptors and Visual Pathways
8.5K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
8.5K
Diabetic Retinopathy
55
DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
55


