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Updated: May 28, 2025

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塞内卡山谷病毒3C蛋白酶分裂HDAC4以对抗I型干扰素信号传递

Zijian Li1,2, Jingjing Yang1,2, Ruiyi Ma1

  • 1Beijing Key Laboratory for Prevention and Control of Infectious Diseases in Livestock and Poultry, Institute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Sciences, Beijing, China.

Journal of virology
|February 10, 2025
PubMed
概括

塞内卡谷病毒通过降解抗病毒蛋白HDAC4.4来逃避宿主免疫力. 病毒3C蛋白酶分裂HDAC4,阻止其限制病毒复制和干扰素信号传递的能力.

关键词:
3C蛋白酶是一种3C蛋白酶.在 HDAC4 中,HDAC4 是塞内卡山谷病毒 (SVV)裂纹 裂纹 裂纹 裂纹第一种类型的干扰素 (IFN-I)

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