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来自Millettia speciosa的多糖化合物香. 通过调节肠道微生物群来改善过度运动引起的疲劳

Jinfeng Zhang¹, Wenkai Zhang¹, Longhui Yu¹

¹Jiangxi Key Laboratory of Natural Product and Functional Food, College of Food Science and Engineering, Jiangxi Agricultural University, Nanchang, China.

Foodborne pathogens and disease

|February 10, 2025

概括

特殊的多糖 (MSP) 通过改善能量储存和抗氧化剂水平来对抗运动引起的疲劳. MSP还积极调节肠道微生物群,建议一种新的疲劳管理方法.

科学领域:

生物化学生物化学
微生物学微生物学
药理学药理学是指药理学的学科.

背景情况:

过度炼会导致疲劳,影响身体表现.
多糖因其生物活性而闻名.
香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 是一种具有潜在药用功能的植物.

研究的目的:

为了研究Millettia speciosa Champ. 的抗疲劳作用. 聚糖 (MSP) 是一种多糖化合物.
描述MSP并评估其抗氧化特性.
确定MSP对运动引起的疲劳和肠道微生物群的影响.

主要方法:

物理化学表征和MSP的体外抗氧化剂测定.
在过度运动的小鼠中评估与疲劳相关的生化标志物.
用MSP治疗的疲劳小鼠的肠道微生物群分析16SrDNA测序.

主要成果:

富含碳水化合物的MSP表现出显著的自由基清除活性.
MSP干预改善了耐力,增加了能量储备 (糖原,ATP,葡萄糖) 和增强了抗氧化剂状态 (GPx,SOD).
MSP降低了疲劳标记 (LDH,CK,BUN) 和调节了肠道微生物群,减少了有害细菌,增加了有益的细菌.

结论:

在暴露于过度运动的小鼠中,MSP表现出显著的抗疲劳作用.
MSP的改善作用与能量代谢和抗氧化能力的改善有关.
MSP可以通过准和调节肠道微生物群组成来发挥其抗疲劳的益处.

关键词:

香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 香 (Millettia speciosa) 聚糖类是一种多糖类.过度运动引起的疲劳.我们的肠道微生物群.物理化学性质表征物理化学性质表征

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