更高的饮食摄入量活微生物与加速的生物衰老相反地相关
Da Gan1, Xiaoyan Wang2, Xuebiao Wu3
1Jiangxi Medicine Academy of Nutrition and Health Management, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China.
Food & function
|February 10, 2025
概括
更高的饮食活微生物摄入量与更慢的生物衰老有关. 消费含有活微生物的食物可能会降低加速衰老过程的风险.
科学领域:
- 营养科学 营养科学
- 老年学是指老年学的学科.
- 微生物学 微生物学
背景情况:
- 生物衰老是一个复杂的过程,受各种因素的影响,包括饮食.
- 饮食中活微生物摄入量对调节生物衰老的作用仍然不完全理解.
- 调查活微生物消费与衰老标志物之间的关联对公共卫生至关重要.
研究的目的:
- 检查饮食中的活微生物摄入量与生物衰老之间的关系.
- 确定高消费活微生物是否与减少生物衰老加速有关.
- 通过两种不同的生物年龄测量方法来探索这种关联.
主要方法:
- 利用了来自NHANES (2007-2010) 的7719名美国成年人 (20岁以上) 的数据.
- 将参与者分为低,中,高饮食活微生物摄入组,并按含有活微生物的食物数量 (MedHi) 分类.
- 使用Klemera-Doubal方法 (KDM-BA) 和表型年龄 (PA) 评估生物年龄,分析KDM-BA和PA加速.
主要成果:
- 饮食中高摄入活微生物与KDM-BA加速的风险降低20%和PA加速的风险降低25%有关.
- 与没有摄入量相比,摄入含有活微生物的食物 (G3) 的较高摄入量显示KDM-BA加速的风险降低了24%,PA加速的风险降低了29% (G1).
- 这些关联在各种人口统计和健康因素中保持一致,包括年龄,性别和先前存在的疾病.
结论:
- 增加饮食中活微生物的摄入量与加速的生物衰老相反地相关.
- 富含活微生物的饮食可能有助于减缓衰老过程.
- 需要进一步研究这种保护作用背后的机制.
更多相关视频
10:39A Suppressor Screen for the Characterization of Genetic Links Regulating Chronological Lifespan in Saccharomyces cerevisiae
Published on: September 17, 2020
6.2K
06:58Author Spotlight: Advancing Caenorhabditis elegans Research Using Paraformaldehyde-Treated Bacteria
Published on: July 28, 2023
2.2K
相关概念视频
01:26Aging
35
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
35
01:37Mitochondria
9.8K
Mitochondria are eukaryotic cellular organelles that are known to produce energy through a process called oxidative phosphorylation. Besides their primary function, mitochondria are involved in various cellular processes, including cell growth, differentiation, signaling, metabolism, and senescence. Age-related changes cause a decline in mitochondrial quality and integrity due to increased mitochondrial mutations and oxidative damage. Thus, aging can severely impact mitochondrial functions,...
9.8K
01:23Anatomy of the Intestines
71.2K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
71.2K