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粘性菌根症患者的治疗结果:回顾性队列研究
Nikhil Gupta1, Ritu Karoli2, Pankaj Verma3
1Additional Professor, Department of General Medicine, Lucknow, Uttar Pradesh, India, Corresponding Author.
The Journal of the Association of Physicians of India
|February 10, 2025
概括
印度面临着高负担的粘膜菌症,通常与不受控制的糖尿病有关. 这项研究发现,犀牛轨道粘膜菌是最常见的,治疗持续时间与血糖控制或铁含量没有显著关联.
科学领域:
- 传染性疾病 传染性疾病
- 菌类学 菌类学是指菌类学.
- 公共卫生 公共卫生
背景情况:
- 在全球范围内,印度的粘性菌病发病率最高,这要归因于失控糖尿病的高发病率和有利的气候.
- 在印度,关于粘膜菌病治疗持续时间和预测结果的数据有限.
- 这项研究调查了疾病程度,血液学/生物化学参数和患者的治疗结果之间的关联.
研究的目的:
- 为了确定粘膜菌的程度和患者的结果之间的关联.
- 探索血液学和生物化学参数与粘膜瘤结局之间的关系.
- 为了提供关于印度背景下菌菌的治疗持续时间的见解.
主要方法:
- 在2021年5月至2021年10月期间入院的100名粘性肌球病患者的回顾性队列研究.
- 通过直接KOH显微镜,组织病理学或真菌培养来确认诊断.
- 排除标准包括混合感染和铁补充剂的使用.
主要成果:
- 犀牛轨道粘膜菌是最常见的类型.
- 糖尿病是最常见的并发症 (85%).
- 平均抗真菌治疗持续时间为30.05±8.34周;观察到血红蛋白/血清铁含量低,血清费里含量高.
结论:
- 失控的糖尿病是一种显著的风险因素,用于粘膜菌.
- 犀牛轨道粘膜菌是主要的形式.
- 治疗持续时间与HbA1C,血清费里或粘性菌类型没有显著关联.
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