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媒介激酶抑制抑制了唐氏综合征中过度活跃的干扰素信号传递

Kira A Cozzolino1, Lynn Sanford2,3, Samuel Hunter2,3

  • 1Department of Biochemistry, University of Colorado, Boulder, United States.

eLife
|February 10, 2025
PubMed
概括

抑制中介激酶CDK8/CDK19通过影响基因表达,新陈代谢和细胞因子,平息了唐氏综合征 (DS) 中的过度活跃的干扰素信号传递. 这一发现为DS和慢性炎症疾病提供了新的治疗策略.

关键词:
唐氏综合征是什么意思 唐氏综合征生物化学 生物化学化学生物学 化学生物学染色体是一种染色体.细胞因子细胞因子基因表达的基因表达方式人类 人类 人类 人类 人类 人类 人类干扰子干扰子干扰子代谢 代谢 代谢 代谢线粒体中的线粒体.

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