NBR1的LC3相互作用区域是一个蛋白相互作用中心,可实现最佳的流量

Brian J North1, Amelia E Ohnstad2, Michael J Ragusa3

  • 1Department of Biochemistry and Cell Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA.

The Journal of cell biology
|February 10, 2025
PubMed
概括

像NBR1这样的自受体使用短线性图案 (SLiM) 结合多个合作伙伴,促进有毒货物的降解. 这项研究揭示了这些图案是多功能交互中心,对于有效的细胞清洁至关重要.

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