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上升的大动脉扩张表明中国心血管疾病患者的阻塞性睡眠呼吸暂停

Luwen Qiu¹, Pingwei Li¹, Zhaohui Ding¹

¹Pulmonary Vascular Diseases Ward, Fuwai Hospital Chinese Academy of Medical Sciences, 12 Langshan Rd, Shenzhen, Shenzhen, Guangdong Province, 518057, China.

Sleep & breathing = Schlaf & Atmung

|February 10, 2025

概括

上升的大动脉直径 (AAD) 可以帮助在心血管疾病 (CVD) 患者中识别阻塞性睡眠呼吸暂停 (OSA). 这种心声回声测量显示出作为查工具的潜力,特别是对于心力衰竭患者.

科学领域:

心脏病学心脏病学
睡眠医学睡眠医学
医疗成像医学成像

背景情况:

阻塞性睡眠呼吸暂停 (OSA) 在心血管疾病 (CVD) 患者中很常见,预后恶化.
早期发现OSA对于及时干预和改善患者结果至关重要.
目前的查方法可能对心血管疾病群体没有完全优化.

研究的目的:

评估通过心声回声计测量的上升大动脉直径 (AAD) 在识别OSA中的实用性.
评估心血管疾病患者AAD和已确定的睡眠呼吸暂停指标之间的相关性.
为了确定AAD在这个队列中用于OSA检测的诊断性能.

主要方法:

对721名住院心血管疾病患者 (高血压,冠状动脉疾病,心力衰竭,心房动,肺高血压) 的回顾性分析.
AAD和睡眠呼吸暂停测试参数之间的相关性分析 (例如,呼吸暂停-呼吸暂停指数[AHI]).
多变量分析和接收器操作者特征 (ROC) 曲线分析,以评估AAD对OSA的预测值.

主要成果:

与没有OSA的患者相比,患有OSA的患者表现出明显更大的AAD.
AAD与AHI和氧和度参数有显著的相关性,与肺动脉直径不同.
ROC分析表明AAD在检测心血管疾病患者的OSA中的有效性 (曲线下的面积[AUC]=0.70) 和心力衰竭小组中的更高AUC (AUC=0.75).

结论:

上升的大动脉直径与心血管疾病患者的OSA严重程度有关.
在心血管疾病患者群体中,AAD作为查OSA的潜在非侵入性工具.
在慢性心力衰竭患者中,AAD在识别OSA方面具有特殊价值.

关键词:

上升的大动脉直径.诊断诊断诊断诊断是一个心声回声图 (Echocardiography) 是一种心声回声图.阻塞性睡眠呼吸暂停症是什么

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