相关实验视频
Updated: May 6, 2026

12:23
Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
10.4K
辛提利马布诱导的光分布型球状皮虫病:一个病例报告
Wenjuan Cui1, Su Wang2, Junzhu Xu2
1Department of Dermatology, Hangzhou Children's Hospital, Hangzhou, Zhejiang, China.
Medicine
|February 10, 2025
概括
免疫检查点抑制剂可能会导致凸骨皮炎 (BP),这是一个罕见的皮肤反应. 早期识别各种BP表现,如光分布,对于管理免疫治疗副作用至关重要.
科学领域:
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
- 皮肤病学 皮肤病学
背景情况:
- 免疫检查点抑制剂 (ICI) 是癌症治疗的关键.
- 免疫疗法诱导的球状皮虫 (BP) 是一种罕见的不良事件.
- 本报告详细介绍了一个与ICI相关的BP.的独特案例.
研究的目的:
- 为了突出一种罕见的免疫疗法诱导的球状皮虫病的呈现.
- 强调早期诊断罕见的免疫相关不良事件.
- 通过及时识别和管理来改善患者的治疗结果.
主要方法:
- 一名患有肺癌的77岁男性接受了sintilimab (抗PD-1).
- 患者在12个月后出现了性湿疹性皮肤炎,16个月后出现了.
- 证实了因辛蒂利马布诱导的球状皮虫的诊断.
主要成果:
- 该患者接受了静脉注射甲基prednisolone和口服prednisone的治疗.
- 皮肤病变显著改善并消失.
- 在19个月的随访期间,没有观察到皮肤病变的复发.
结论:
- 由PD-1/PD-L1抑制剂诱导的牛性皮虫症可以呈现出各种临床特征.
- 皮肤科医生必须在接受ICI治疗的患者中保持高血压怀疑指数.
- 对各种表现的认识对于及时诊断和有效管理至关重要.
相关概念视频
Skin Diseases and Disorders
5.4K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.4K
Bacterial Phylum Spirochaetes
1.5K
Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased...
1.5K
Diversity of Protists I
2.3K
Excavata is a diverse group of protists that includes both chemoorganotrophic and phototrophic species, with some thriving in anaerobic environments. Among the key groups within Excavata are diplomonads and parabasalids, which are flagellated protists that lack mitochondria and chloroplasts. These microorganisms typically inhabit anoxic environments, such as the intestines of animals, where they exist either symbiotically or as parasites, relying on fermentation for energy production. Some...
2.3K
Diversity of Protists II
2.3K
Alveolates are a group of organisms recognized by the presence of alveoli, which are cytoplasmic sacs located beneath the cell membrane. While their function remains uncertain, alveoli may help regulate water balance by controlling how much water enters and leaves the cell. In dinoflagellates, these structures may serve as armor plates. There are three major types of alveolates: ciliates, which move using cilia; dinoflagellates, which use flagella for movement; and apicomplexans, which are...
2.3K

