功能性分鼻整形在改善COVID-19相关的嗅觉功能障碍方面的有效性
Alfonso Luca Pendolino1,2, Bruno Scarpa3, Peter J Andrews1,2
1Department of ENT, Royal National ENT & Eastman Dental Hospitals, London, United Kingdom.
Facial plastic surgery : FPS
|February 10, 2025
概括
与嗅觉训练相比,功能性分鼻整形 (fSRP) 显著改善了长期的COVID-19嗅觉功能障碍. 接受fSRP治疗的患者表现出显著的嗅觉值增长,为持久性C19OD提供了一种新的治疗途径.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 神经学 神经学
- 传染性疾病 传染性疾病
背景情况:
- 在COVID-19 (C19OD) 后持续的嗅觉功能障碍是一个重大的临床挑战.
- 目前对C19OD的治疗方法缺乏确定的疗效.
- 迫切需要有效的干预措施来恢复嗅觉功能.
研究的目的:
- 评估功能性分泌膜整形术 (fSRP) 对改善持续性C19OD患者的嗅觉功能障碍的有效性.
- 将fSRP的结果与管理C19OD的嗅觉训练 (OT) 进行比较.
- 在干预后评估嗅觉功能和鼻气流参数.
主要方法:
- 一项前性研究,将fSRP与为持久性C19OD接受OT的对照组进行比较.
- 使用嗅探棒 (S'S) 评估嗅觉功能,通过峰鼻吸气流 (PNIF) 和声学鼻测 (AR) 评估鼻气流.
- 六个月的随访期来评估治疗的疗效.
主要成果:
- 与对照组不同的是,fSRP组在所有S'S分数中显示出显著的改善 (p < 0.05).
- 仅在fSRP组中,TDI得分超过了临床重要差异的最小值.
- 与OT组相比,fSRP组观察到显著的嗅觉值增长.
结论:
- 功能性分鼻整形 (fSRP) 对患有持续COVID-19相关的嗅觉功能障碍的患者提供了显著的治疗益处.
- fSRP导致嗅觉功能的显著改善和值的增加.
- 这种手术方法为C19OD管理提供了对嗅觉培训的有希望的替代方案.
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