生命的基本8和美国成年人患有关节炎的所有原因和心血管死亡的风险:使用NHANES数据库进行回顾性队列研究
Feiyu Yao1, Jiafeng Zhang2, Xianhua Li3,4
1Pediatric Hospital, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.
International journal of rheumatic diseases
|February 10, 2025
概括
使用Life's Essential 8 (LE8) 改善心血管健康显著降低了美国成年关节炎患者的死亡风险. 较高的LE8得分与减少所有原因和心血管疾病死亡率相关.
科学领域:
- 心血管健康 心血管健康
- 流行病学 流行病学
- 类风湿病学 类风湿病学
背景情况:
- 生命的基本8 (LE8) 是评估心血管健康 (CVH) 的关键指标.
- 关节炎是一种普遍的疾病,与死亡风险增加有关.
- 在关节炎患者群体中,LE8与死亡率之间的关系需要进行研究.
研究的目的:
- 为了检查生命的基本8 (LE8) 评分和死亡风险之间的关联.
- 评估美国成年人被诊断患有关节炎的心血管健康 (CVH).
- 确定LE8对该群体内所有原因和心血管疾病 (CVD) 死亡率的影响.
主要方法:
- 使用美国国家健康和营养检查调查 (NHANES) 数据 (2005-2018) 的回顾性队列研究.
- 包括患有关节炎的参与者,与国家死亡记录相关的死亡数据.
- 分析使用卡普兰-梅尔曲线和加权考克斯比例危险回归模型来评估死亡风险.
主要成果:
- 在LE8得分中增加10个点与所有原因死亡率降低17%,心血管疾病死亡率降低25%有关.
- 与最低类别相比,LE8 CVH最高类别的个体具有38%较低的全因死亡风险和62%较低的心血管疾病死亡风险.
- 卡普兰-梅尔曲线表明,高CVH的个体的生存概率显著更高.
结论:
- 对生活必需品8 (LE8) 建议的更高遵守与死亡率的降低有关.
- 在关节炎患者的风险分层和管理中,LE8是一个有价值的工具.
- 促进最佳的心血管健康对于改善关节炎患者的生存结果至关重要.
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