米托素2在蛋白质稳定监测中表现出与聚变无关的作用

Mariana Joaquim1,2,3, Selver Altin1,2, Maria-Bianca Bulimaga1,2,3,4

  • 1Institute for Genetics, University of Cologne, Cologne, Germany.

Nature communications
|February 10, 2025
PubMed
概括

米托素2 (MFN2) 作为细胞蛋白质稳定的一个关键守门员,防止蛋白质聚合,无论其在线粒体形状中的作用如何. 这一发现为针对MFN2.2的治疗提供了新的途径.

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