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Updated: May 28, 2025

NF-κB-dependent Luciferase Activation and Quantification of Gene Expression in Salmonella Infected Tissue Culture Cells
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Published on: January 12, 2020

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NF-κB RelB通过与RelA竞争,以结合目标基因促进体而抑制树突细胞的炎症基因表达程序

Héctor I Navarro1,2, Allison E Daly1,2, Benancio Rodriguez1,2

  • 1Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA, USA.

Cell discovery
|February 10, 2025
PubMed
概括

RelB作为促炎基因的关键抑制剂,预防自身免疫性疾病. 失去RelB功能导致RelA结合增加和基因表达升高,导致炎症病理.

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