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Updated: May 28, 2025

Isolation of Primary Mouse Hepatocytes for Nascent Protein Synthesis Analysis by Non-radioactive L-azidohomoalanine Labeling Method
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KMT5C调节肝脏葡萄糖生成的非催化机制

Qingwen Zhao1,2, Xuan Cui1, Qi Zhu1

  • 1Key Laboratory of Metabolism and Molecular Medicine of the Ministry of Education, Department of Biochemistry and Molecular Biology of School of Basic Medical Sciences, Fudan University, Shanghai, China.

Nature communications
|February 10, 2025
PubMed
概括

氨酸甲基转移酶KMT5C通过稳定PGC-1α,独立于其甲基转移酶活性来调节肝脏葡萄糖的产生. 这一发现为糖尿病患者的血糖水平管理提供了新的见解.

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