食补充剂和预防妊娠前症
Takafumi Ushida1,2, Sho Tano3,4, Seiko Matsuo3,4
1Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan. u-taka23@med.nagoya-u.ac.jp.
预防产前 (PE) 非常重要,因为有效的治疗方法有限. 像这样的食补充剂显示出有前途,但对像维生素D这样的其他补充剂来说,需要更多的研究来降低PE风险.
科学领域:
- 产科和妇科 产科和妇科
- 营养科学 营养科学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
背景情况:
- 孕前 (PE) 是一种严重的妊娠并发症,除了分娩外,没有确定的治疗方法.
- 对于PE的预防策略越来越重要.
- 食补充剂正在作为预防PE的非药理学方法进行研究.
研究的目的:
- 审查关于预防产前的食补充剂的证据.
- 提供各种补充剂及其有效性的全面概述.
- 为制定更好的PE预防策略提供信息.
主要方法:
- 对预防PE的食补充剂现有的文献进行系统审查.
- 对,维生素D和其他维生素,矿物质,氨基酸,抗氧化剂和脂肪酸的证据分析.
- 评估系统审查和元分析的发现.
主要成果:
- 补充 (每天500毫克) 在摄入低的人群中显著降低PE风险.
- 关于维生素D在PE预防中的有效性的证据不一致,需要进一步的大规模试验.
- 广泛的其他补充剂 (维生素,矿物质,氨基酸,抗氧化剂,omega-3脂肪酸) 被审查了不同程度的证据.
结论:
- 是风险人群中PE预防的成熟补充剂.
- 维生素D需要更多的研究来证实其在PE预防中的作用.
- 对食补充剂的全面了解可以帮助制定有效的PE预防策略.
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