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Updated: Jun 15, 2026

Author Spotlight: Understanding Disease Mechanisms Through Real-Time Analysis of T-Cell Migration
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Published on: May 24, 2024

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将T细胞动态映射到分子配置文件,通过行为引导的转录学.

A K L Wezenaar1,2, U Pandey1,2, F Keramati1

  • 1Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands.

Nature protocols
|February 10, 2025
PubMed
概括

这项研究引入了行为引导转录学 (BGT),将实时成像与单细胞RNA测序相结合,以将T细胞行为与其基因表达联系起来. 这种方法可以识别生物标志物,以提高癌症免疫疗法的有效性.

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