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Updated: May 12, 2026

Improved Lipofuscin Models and Quantification of Outer Segment Phagocytosis Capacity in Highly Polarized Human Retinal Pigment Epithelial Cultures
10:39

Improved Lipofuscin Models and Quantification of Outer Segment Phagocytosis Capacity in Highly Polarized Human Retinal Pigment Epithelial Cultures

Published on: April 14, 2023

探索ABCA4的ECD2域在遗传性视网膜退化中的作用:计算和功能视角

Jazzlyn S Jones1,2, Subhasis B Biswas1,2, Esther E Biswas-Fiss3,4

  • 1Department of Medical and Molecular Sciences, College of Health Sciences, University of Delaware, Newark, DE, USA.

Advances in experimental medicine and biology
|February 10, 2025
PubMed
概括

在ABCA4基因的遗传变异导致遗传性视网膜发育不良通过损害视网膜体的运输. 这项研究确定了ABCA4外细胞质域 (ECD2) 中的关键集群,这些集群对于视网结合和功能至关重要.

关键词:
在ABCA4A4A4A4A4A4A4A4A4计算方法 计算方法在 ECD2 中使用.遗传性视网膜疾病 (IRD) 是一种遗传性视网膜疾病.

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