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Updated: May 28, 2025

A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development
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A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development

Published on: February 11, 2019

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10毫克甲基酸盐对健康成年人的认知表现和视觉扫描的急性施用:随机,双盲,安慰剂控制的随机研究

Blair Aitken1, Luke A Downey1,2, Serah Rose1

  • 1Centre for Mental Health and Brain Sciences, Swinburne University of Technology, Hawthorn, Australia.

Human psychopharmacology
|February 11, 2025
PubMed
概括

低剂量甲基 (10毫克) 改善了健康成年人的数值工作记忆准确度,但没有影响视觉扫描效率. 这表明,对于一般认知增强,具有有限的亲认知益处.

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Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD

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Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
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Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
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To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
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